1. 1. Name of disease: Aplastic anemia.

Root cause of disease:
The causes of Aplastic anemia are when damage occurs to your bone marrow, slowing or shutting down the production of new blood cells. In pregnant cases Aplastic anemia can be causes by autoimmune disorder. Idiopathic Aplastic Anemia on the other hand is when there is no known cause, doctors themselves do not know how this disease occurred. Aplastic anemia affects leukocytes, Erythrocytes and thrombocytes.

Affected cell types/tissues/organs/systems: This actually affect each and every tissue in the body if there is an under production of red blood cells the body suffers the lack of oxygen, which can cause complications. With Leukocytes there is an underproduction of them which is also dangerous because the lack of white blood cells can cause serious infections, immunosuppression and the most dangerous, leukemia. Thrombocytes on the other hand with an underproduction of thrombocytes the body takes a long time to heal and you have a lot of bleeding problems.


Historical background: (Include discoverer(s), famous victims, and
any historical events linked to the disease).
The actual discovery of Aplastic anemia is unknown, but articles state that it was discovered by a young physician named Ehrlich. It was discovered when he realized a woman had a severe case of pancytopenia which happens in Aplastic anemia and realized that her bone marrow was yellow instead of that reddish you see with anemia patients. This was actually a weird discovery because they don’t know who actually discovered this disease. Marie Curie is a famous woman who died from aplastic anemia. She was the lady who discovered radium.


Symptoms :
The common symptoms of Aplastic anemia are fatigue, shortness of breath, irregular or rapid heartbeat, pale skin, and easy bruising.


Treatments
Some of the treatments for aplastic anemia are bone marrow transplants, Oxymetholone, and Anadrol-50 oral. Current research that they are trying to do is on adolescents and young adults and they are trying to find different ways to treat this disease.

Other research
Also they are also doing research for moderate use of cyclophosphamide for severe aplastic anemia to see if it does much of anything.
References: http://www.mayoclinic.org/diseases-conditions/aplastic-anemia/basics/causes/con-20019296
http://www.webmd.com/drugs/condition-838-Aplastic+Anemia.aspx?..
http://www.haematologica.org/content/80/3/294
http://www.ncbi.nlm.nih.gov/pubmed/25228559
This Diagram Shows the cells affected in Aplastic anemia


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